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NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

National Institutes of Health Nonprofit eligible

National Institutes of Health is funding education projects through this opportunity, which is open to nonprofits and other eligible applicants, with applications due Jan 7, 2028.

Open the official Grants.gov listing
Deadline
Jan 7, 2028
Posted
Dec 18, 2024
Opportunity number
PA-25-306
CFDA
93.113, 93.143, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.855, 93.865, 93.866, 93.867, 93.879

Opportunity description

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.Applicants should note that some ICs (see Related Notices) only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this funding opportunity announcement.

Who can apply

  • Public housing authorities/Indian housing authorities
  • For profit organizations other than small businesses
  • County governments
  • Special district governments
  • Private institutions of higher education
  • City or township governments
  • State governments
  • Public and State controlled institutions of higher education
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Small businesses
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Agency contact

National Institutes of Health

NIH Grants Information grantsinfo@nih.gov

grantsinfo@nih.gov

Next steps to apply

This award is administered through the federal Grants.gov system. Review the complete instructions and verify the deadline on the official page before starting your submission.

Official Grants.gov listing

We summarize this opportunity from the public Grants.gov database for convenience. It is general information, not legal or grant advice. VolunteerBadge is not affiliated with any agency — rely on the official listing for final details and deadlines.

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