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NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

National Institutes of Health Nonprofit eligible

Here's an active health funding opportunity from National Institutes of Health, open to nonprofits and other eligible applicants, with applications due Jan 7, 2027. It provides awards up to $1.5M.

Open the official Grants.gov listing
Deadline
Jan 7, 2027
Award amount
Up to $1.5M
Posted
Dec 5, 2024
Opportunity number
PAR-25-025
CFDA
93.233, 93.837, 93.838, 93.839

Opportunity description

The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be established by the time of award. If time and support for these and other pre-clinical and/or trial readiness activities are desired, applicants should consider the companion NOFO which utilizes an R61/R33 phased approach.

Who can apply

  • Special district governments
  • Small businesses
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public and State controlled institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • State governments
  • City or township governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • County governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Independent school districts
  • For profit organizations other than small businesses
  • Native American tribal governments (Federally recognized)
  • Public housing authorities/Indian housing authorities
  • Private institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

Award ceiling
$1.5M

Agency contact

National Institutes of Health

NIH Grants Information grantsinfo@nih.gov

grantsinfo@nih.gov

Next steps to apply

You will apply through Grants.gov, the federal grants portal. Confirm every detail — eligibility, attachments, and the deadline — on the official page before you commit time to it.

Official Grants.gov listing

We summarize this opportunity from the public Grants.gov database for convenience. It is general information, not legal or grant advice. VolunteerBadge is not affiliated with any agency — rely on the official listing for final details and deadlines.

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