Open — closes in 487 days

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)

National Institutes of Health Nonprofit eligible

This open federal grant from National Institutes of Health supports health-focused work and is available to nonprofits and other eligible applicants, with applications due Oct 20, 2027.

Go to the Grants.gov listing
Deadline
Oct 20, 2027
Posted
Nov 4, 2024
Opportunity number
PAR-25-225
CFDA
93.853

Opportunity description

Reissue PAR-21-122. This NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate that proposed therapeutic agent(s) have sufficient biological activity to warrant further development to treat neurological or neuromuscular disorders that fall under the NINDS mission. Therapeutic agents include small molecules, biologics or biotechnology-derived products. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.

Who can apply

  • Native American tribal governments (Federally recognized)
  • Private institutions of higher education
  • Special district governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Independent school districts
  • State governments
  • Public and State controlled institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • County governments
  • For profit organizations other than small businesses
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • City or township governments
  • Small businesses
  • Public housing authorities/Indian housing authorities

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Agency contact

National Institutes of Health

NIH Grants Information grantsinfo@nih.gov

grantsinfo@nih.gov

Applying for this grant

Submission is handled entirely on Grants.gov. Open the official listing below to see the full notice, required forms, and the authoritative deadline.

Official Grants.gov listing

We summarize this opportunity from the public Grants.gov database for convenience. It is general information, not legal or grant advice. VolunteerBadge is not affiliated with any agency — rely on the official listing for final details and deadlines.

Need cleared volunteers for your funded program?

VolunteerBadge runs FCRA-compliant, identity-verified background checks for $5 — fast and affordable enough for any grant timeline.

See how it works

Related grant opportunities