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Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)

National Institutes of Health Nonprofit eligible

This open federal grant from National Institutes of Health supports health-focused work and is available to nonprofits and other eligible applicants, with applications due Jan 11, 2027.

Open the official Grants.gov listing
Deadline
Jan 11, 2027
Posted
Jun 18, 2026
Opportunity number
PAR-27-071
CFDA
93.310

Opportunity description

As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First Program), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program supported genomic data generating centers. Applicants are encouraged to propose sequencing of existing pediatric cancer or congenital anomaly cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, to investigate the genetic etiology of congenital anomalies, to study the molecular basis of the associations between congenital anomalies and increased cancer risk, or to expand the range of pediatric disorders included within the Kids First Data Resource. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as clinical-grade sequencing, long-read sequencing, proteomics, and epigenomic assays of tumor or affected tissue, when justified. Applicants are encouraged to propose cohorts to increase representation of existing Kids First Program projects. These data, and associated clinical and phenotypic data, will become part of the Kids First Data Resource Center for sharing with the research community.

Who can apply

  • Public housing authorities/Indian housing authorities
  • County governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • State governments
  • Small businesses
  • For profit organizations other than small businesses
  • Native American tribal governments (Federally recognized)
  • Private institutions of higher education
  • Special district governments
  • City or township governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Agency contact

National Institutes of Health

Gabriella Miller Kids First Program kidsfirst@od.nih.gov

kidsfirst@od.nih.gov

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Official Grants.gov listing

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