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Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

National Institutes of Health Nonprofit eligible

This open federal grant from National Institutes of Health supports education-focused work and is available to nonprofits and other eligible applicants, with applications due Jan 7, 2028.

View & apply on Grants.gov
Deadline
Jan 7, 2028
Posted
Nov 6, 2024
Opportunity number
PAR-25-145
CFDA
93.393

Opportunity description

The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae. Research projects should focus on mechanistic studies with translational endpoints and longitudinal clinical phenotyping to identify and validate clinical endpoints (biomarkers, imaging, patient-reported outcomes, or combined elements) for future use in clinical trials that will evaluate the efficacy of interventions designed to prevent or reduce specific adverse sequelae.

Who can apply

  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Special district governments
  • Public housing authorities/Indian housing authorities
  • Native American tribal governments (Federally recognized)
  • Small businesses
  • For profit organizations other than small businesses
  • Private institutions of higher education
  • Independent school districts
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • State governments
  • City or township governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • County governments
  • Public and State controlled institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Agency contact

National Institutes of Health

NIH Grants Information grantsinfo@nih.gov

grantsinfo@nih.gov

Where to apply

Applications go through Grants.gov directly. We recommend reading the full announcement and double-checking eligibility and dates on the official listing first.

Official Grants.gov listing

Information here comes from the public Grants.gov dataset, which is U.S. government public-domain data, and is shared for general guidance only. VolunteerBadge neither administers grants nor speaks for any agency — confirm everything on the official listing before applying.

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