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Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)

National Institutes of Health Nonprofit eligible

National Institutes of Health has posted this health grant for nonprofits and other eligible applicants, with applications due May 28, 2027. It provides awards up to $3.5M.

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Deadline
May 28, 2027
Award amount
Up to $3.5M
Posted
Oct 2, 2026
Opportunity number
RFA-AI-28-031
CFDA
93.310, 93.855

Opportunity description

The purpose of this notice of funding opportunity (NOFO) is to support multidisciplinary consortia of structural biologists, microbiologists, and associated experts to solve complex biological structures related to the prevention, treatment, and cure of HIV and other infectious diseases. Centers are expected to facilitate new collaborations, leverage shared resources, offer services and resources to the research community, and train the next generation of scientists engaged in structural biology of infectious diseases.

Who can apply

  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • For profit organizations other than small businesses
  • County governments
  • Native American tribal governments (Federally recognized)
  • City or township governments
  • Private institutions of higher education
  • State governments
  • Special district governments
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Independent school districts
  • Public housing authorities/Indian housing authorities
  • Public and State controlled institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Small businesses

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Funding

Award ceiling
$3.5M

Agency contact

National Institutes of Health

National Institute of Allergy and Infectious Diseases (NIAID) BSPDAIDSNOFO@mail.nih.gov

BSPDAIDSNOFO@mail.nih.gov

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