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Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

National Institutes of Health Nonprofit eligible

This open federal grant from National Institutes of Health supports health-focused work and is available to nonprofits and other eligible applicants, with applications due Oct 19, 2026. It provides awards up to $50K–$600K.

View & apply on Grants.gov
Deadline
Oct 19, 2026
Award amount
Up to $50K–$600K
Expected awards
2
Posted
May 21, 2026
Opportunity number
RFA-CA-27-021
CFDA
93.393, 93.394, 93.395, 93.396, 93.399

Opportunity description

This Notice of Funding Opportunity (NOFO) solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to early-stage and advanced development efforts to generate these tools and resources that will be supported by companion ITCR NOFOs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the application must provide clear justification for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field. In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting close engagement between the resource and the targeted research community should be described.This NOFO invites applications to support the sustained operations of informatics technology resources that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on sustaining resources that have had a demonstrated impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Evidence that the technology has had significant impact on cancer research to date and the sustainment plan will lead to the continued advancement of cancer researchRobust plans for supporting the end-user community including documentation, training, and other outreach activitiesClear processes for engaging end users to address emerging needs of the targeted research communities to ensure that the research resource maintains relevance to the research it supports

Who can apply

  • Private institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • For profit organizations other than small businesses
  • Independent school districts
  • County governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Small businesses
  • Public and State controlled institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Special district governments
  • Public housing authorities/Indian housing authorities
  • City or township governments
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • State governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

Award floor
$50K
Award ceiling
$600K

Agency contact

National Institutes of Health

Center for Strategic Scientific Initiatives (CSSI) nciitcr@mail.nih.gov

nciitcr@mail.nih.gov

Where to apply

Submission is handled entirely on Grants.gov. Open the official listing below to see the full notice, required forms, and the authoritative deadline.

Official Grants.gov listing

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