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Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

National Institutes of Health Nonprofit eligible

Administered by National Institutes of Health, this health grant invites applications from nonprofits and other eligible applicants, with applications due Jul 1, 2028. It provides awards up to $50K–$400K.

Apply on Grants.gov
Deadline
Jul 1, 2028
Award amount
Up to $50K–$400K
Posted
Jun 25, 2026
Opportunity number
PAR-27-021
CFDA
93.310, 93.351, 93.855, 93.866

Opportunity description

This Notice of Funding Opportunity (NOFO) aims to build new research capacity and develop a sustainable research program by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.

Who can apply

  • Independent school districts
  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • State governments
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Public and State controlled institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • For profit organizations other than small businesses
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Small businesses
  • Native American tribal governments (Federally recognized)
  • Special district governments
  • Private institutions of higher education
  • County governments
  • City or township governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Funding

Award floor
$50K
Award ceiling
$400K

Agency contact

National Institutes of Health

Office of Research Infrastructure Programs (ORIP) odsig@mail.nih.gov

odsig@mail.nih.gov

Where to apply

Submission is handled entirely on Grants.gov. Open the official listing below to see the full notice, required forms, and the authoritative deadline.

Official Grants.gov listing

Information here comes from the public Grants.gov dataset, which is U.S. government public-domain data, and is shared for general guidance only. VolunteerBadge neither administers grants nor speaks for any agency — confirm everything on the official listing before applying.

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