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NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

National Institutes of Health Nonprofit eligible

Here's an active health funding opportunity from National Institutes of Health, open to nonprofits and other eligible applicants, with applications due Sep 3, 2026.

View & apply on Grants.gov
Deadline
Sep 3, 2026
Expected awards
7
Posted
Jun 29, 2026
Opportunity number
RFA-RM-27-003
CFDA
93.310

Opportunity description

The NIH Director"s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director"s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Who can apply

  • Public housing authorities/Indian housing authorities
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Special district governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • County governments
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • City or township governments
  • Small businesses
  • State governments
  • Public and State controlled institutions of higher education

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Agency contact

National Institutes of Health

NIH Director's Transformative Research Award Program Transformative_Awards@mail.nih.gov

Transformative_Awards@mail.nih.gov

How to apply

To apply, head to the official Grants.gov listing — that is where registration and submission happen. Always re-check the closing date there, as agencies can revise it.

Official Grants.gov listing

This listing is sourced from the public Grants.gov database (U.S. government public-domain data) and is provided for general informational purposes. VolunteerBadge is not affiliated with Grants.gov or any federal agency and does not administer or award grants. Always verify details on the official listing.

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