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Metastasis Research Network (U54 Clinical Trial Not Allowed)

National Institutes of Health Nonprofit eligible

Looking for health funding? National Institutes of Health is accepting applications for this award from nonprofits and other eligible applicants, with applications due Sep 25, 2026. It provides awards up to $1.3M.

Go to the Grants.gov listing
Deadline
Sep 25, 2026
Award amount
Up to $1.3M
Expected awards
4
Posted
Jun 4, 2026
Opportunity number
RFA-CA-27-012
CFDA
93.396

Opportunity description

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on developing a comprehensive and cohesive understanding of cancer metastasis. Towards this goal, the NCI will support U54 Specialized Centers that together will continue to serve as the hub of the Metastasis Research Network (MetNet). Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multidisciplinary basic research projects. The projects should use integrative system level approaches to elucidate and integrate a mechanistic understanding of the non-linear, dynamic, and emergent processes in metastasis. Overarching themes should encompass the interplay between at least two central elements in the metastatic process such as early dissemination, cellular, soluble and/or physical microenvironment crosstalk, dormancy, or mechanisms of responses by metastatic cells to therapies. Studies on all types of cancer are welcome, including rare and pediatric metastatic cancers.Research proposed by MetNet Centers is expected to advance our understanding towards a more comprehensive appreciation of metastasis as a whole body, systems-level problem.

Who can apply

  • State governments
  • Native American tribal governments (Federally recognized)
  • Independent school districts
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Public housing authorities/Indian housing authorities
  • City or township governments
  • Special district governments
  • County governments
  • Small businesses
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Public and State controlled institutions of higher education
  • For profit organizations other than small businesses

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

Award ceiling
$1.3M

Agency contact

National Institutes of Health

NCI MetNet Research Program NCIMetNet@mail.nih.gov

NCIMetNet@mail.nih.gov

Next steps to apply

To apply, head to the official Grants.gov listing — that is where registration and submission happen. Always re-check the closing date there, as agencies can revise it.

Official Grants.gov listing

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