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Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

National Institutes of Health Nonprofit eligible

Administered by National Institutes of Health, this health grant invites applications from nonprofits and other eligible applicants, with applications due Oct 19, 2026. It provides awards up to $50K–$600K.

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Deadline
Oct 19, 2026
Award amount
Up to $50K–$600K
Expected awards
3
Posted
May 21, 2026
Opportunity number
RFA-CA-27-020
CFDA
93.393, 93.394, 93.395, 93.396, 93.399

Opportunity description

This Notice of Funding Opportunity (NOFO) invites applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, analysis, visualization, and interpretation of data across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on advancing emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. To be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving cancer research projects as well as the broader user community throughout the development process must be included.This NOFO invites applications for the enhancement and dissemination of emerging, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Potential to advance driving cancer research projects and the cancer research field in general;Offers clear advantages over competing technologies in the targeted cancer research domain;Provides compelling plans and processes for supporting and engaging end users to evaluate and apply the tool or resource;Provides plans for advancing use of the tool or resource by the targeted community through collaboration, outreach, and training;Provides a realistic timeline and milestones for technology development.

Who can apply

  • Public housing authorities/Indian housing authorities
  • Native American tribal governments (Federally recognized)
  • State governments
  • County governments
  • Special district governments
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Small businesses
  • City or township governments
  • Public and State controlled institutions of higher education
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • Independent school districts
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

Award floor
$50K
Award ceiling
$600K

Agency contact

National Institutes of Health

Center for Strategic Scientific Initiatives (CSSI) nciitcr@mail.nih.gov

nciitcr@mail.nih.gov

Where to apply

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