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NIH Director’s New Innovator Award (DP2 Clinical Trial Optional)

National Institutes of Health Nonprofit eligible

National Institutes of Health has posted this health grant for nonprofits and other eligible applicants, with applications due Aug 17, 2026. It provides awards up to $475K.

Go to the Grants.gov listing
Deadline
Aug 17, 2026
Award amount
Up to $475K
Expected awards
30
Posted
Jun 26, 2026
Opportunity number
RFA-RM-27-002
CFDA
93.310

Opportunity description

The NIH Director"s New Innovator Award supports early-stage investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. The NIH Director's New Innovator Award complements other ongoing efforts by NIH and its Institutes and Centers to fund early-stage investigators. The NIH Director"s New Innovator Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Who can apply

  • State governments
  • Public and State controlled institutions of higher education
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Native American tribal governments (Federally recognized)
  • For profit organizations other than small businesses
  • Small businesses
  • County governments
  • Public housing authorities/Indian housing authorities
  • City or township governments
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Independent school districts
  • Private institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • Special district governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Funding

Award floor
$475K
Award ceiling
$475K

Agency contact

National Institutes of Health

NIH Director's New Innovator Award Program NewInnovatorAwards@mail.nih.gov

NewInnovatorAwards@mail.nih.gov

Applying for this grant

Submission is handled entirely on Grants.gov. Open the official listing below to see the full notice, required forms, and the authoritative deadline.

Official Grants.gov listing

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