Open — closes in 1070 days

NIAID Investigator Initiated Program Project Applications (P01 Clinical Trial Not Allowed)

National Institutes of Health Nonprofit eligible

This open federal grant from National Institutes of Health supports health-focused work and is available to nonprofits and other eligible applicants, with applications due May 25, 2029.

See full details on Grants.gov
Deadline
May 25, 2029
Posted
May 7, 2026
Opportunity number
PAR-27-082
CFDA
93.855

Opportunity description

This notice of funding opportunity (NOFO) invites submission of investigator-initiated Program Project (P01) applications. The proposed Programs should address scientific areas relevant to the NIAID mission including: biology and pathogenesis of infectious microbes, including HIV; host-microbe interactions; mechanisms regulating immune system development and function across the lifespan, and in response to infectious pathogens; immune dysfunction resulting in allergy, asthma, autoimmunity, immunodeficiency, or transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious and immune-mediated diseases. Each application submitted to this NOFO must include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; and an Administrative Core. An application may include Scientific Core(s), if needed for the proposed research.

Who can apply

  • Public and State controlled institutions of higher education
  • Small businesses
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Native American tribal governments (Federally recognized)
  • State governments
  • Independent school districts
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Others (see text field entitled "Additional Information on Eligibility" for clarification)
  • City or township governments
  • Special district governments
  • Public housing authorities/Indian housing authorities
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • For profit organizations other than small businesses
  • County governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Agency contact

National Institutes of Health

National Institute of Allergy and Infectious Diseases (NIAID) NIAID_P01_NOFO@mail.nih.gov

NIAID_P01_NOFO@mail.nih.gov

Applying for this grant

Applications go through Grants.gov directly. We recommend reading the full announcement and double-checking eligibility and dates on the official listing first.

Official Grants.gov listing

Grant details are pulled from the public-domain Grants.gov feed and are offered for general information. VolunteerBadge is independent of Grants.gov and all federal agencies; the official listing is always the authoritative source.

Need cleared volunteers for your funded program?

VolunteerBadge runs FCRA-compliant, identity-verified background checks for $5 — fast and affordable enough for any grant timeline.

See how it works

Keep browsing related grants